A
NFL
James Cook
+110Fanatics
Anytime TD
- Estimated edge
- 7.9%
- Fair odds
- -125
- Starts
- 9/17 - 8:15 PM EDT
NFL game preview
Detroit Lions at Buffalo Bills
projected score, fair-odds context, available venue conditions, and current value for this matchup.
Game details
Starts9/17 - 8:15 PM EDT
VenueHighmark Stadium · Orchard Park, NY, USA
Game-time weather73°F · ThunderstormsRain 88%
Market coverage5 tracked opportunitiesUpdated Sep 14, 9:14 AM EDT
Market read
Matchup outlook
The market-implied score favors Buffalo Bills 28.7–24.7 over Detroit Lions, a 4.0-point margin. The consensus total is 53.4, with Buffalo Bills -4 at home.
At Highmark Stadium, the game-time forecast is 73°F and thunderstorms, with a 88% chance of precipitation.
Player markets
Current player prop edges
Confirm player availability and the latest line before placing a bet.
A
NFL
Amon-Ra St. Brown
+155Fanatics
Anytime TD
- Estimated edge
- 4.5%
- Fair odds
- +129
- Starts
- 9/17 - 8:15 PM EDT
A
NFL
Jameson Williams
+265Fanatics
Anytime TD
- Estimated edge
- 3.8%
- Fair odds
- +221
- Starts
- 9/17 - 8:15 PM EDT
A
NFL
Jahmyr Gibbs
-250Fanatics
Anytime TD
- Estimated edge
- 3.5%
- Fair odds
- -299
- Starts
- 9/17 - 8:15 PM EDT
A
NFL
Sam LaPorta
+340Fanatics
Anytime TD
- Estimated edge
- 3.0%
- Fair odds
- +288
- Starts
- 9/17 - 8:15 PM EDT