A
NFL
Christian McCaffrey
+440FanDuel
last td
- Estimated edge
- 4.0%
- Fair odds
- +345
- Starts
- Sep 27, 4:05 PM EDT
NFL game preview
Arizona Cardinals at San Francisco 49ers
projected score, fair-odds context, available venue conditions, and current value for this matchup.
Game details
StartsSep 27, 2026, 4:05 PM EDT
Market coverage27 tracked opportunitiesUpdated Sep 24, 1:22 AM EDT
Market read
Matchup outlook
The market-implied score favors San Francisco 49ers 27.6–19.1 over Arizona Cardinals, a 8.5-point margin. The consensus total is 46.8, with San Francisco 49ers -8.5 at home.
Player markets
Current player prop edges
Confirm player availability and the latest line before placing a bet.
A
NFL
Tyler Allgeier
+100theScore
Over 34.5 rush yds
- Estimated edge
- 3.3%
- Fair odds
- -114
- Starts
- Sep 27, 4:05 PM EDT
A
NFL
Brock Purdy
+325BetMGM
Anytime TD
- Estimated edge
- 3.1%
- Fair odds
- +276
- Starts
- Sep 27, 4:05 PM EDT
B
NFL
Christian McCaffrey
-235BetMGM
Anytime TD
- Estimated edge
- 2.6%
- Fair odds
- -267
- Starts
- Sep 27, 4:05 PM EDT
B
NFL
Marvin Harrison Jr.
+100theScore
Under 29.5 reception yds
- Estimated edge
- 2.6%
- Fair odds
- -111
- Starts
- Sep 27, 4:05 PM EDT
B
NFL
Michael Wilson
+128betPARX
Under 3.5 receptions
- Estimated edge
- 2.2%
- Fair odds
- +117
- Starts
- Sep 27, 4:05 PM EDT
B
NFL
Christian McCaffrey
+335BetRivers
1st td
- Estimated edge
- 2.1%
- Fair odds
- +299
- Starts
- Sep 27, 4:05 PM EDT
C
NFL
Jeremiyah Love
+1100theScore
1st td
- Estimated edge
- 1.8%
- Fair odds
- +889
- Starts
- Sep 27, 4:05 PM EDT
C
NFL
George Kittle
+1200theScore
1st td
- Estimated edge
- 1.8%
- Fair odds
- +957
- Starts
- Sep 27, 4:05 PM EDT
C
NFL
Tyler Allgeier
+1200Hard Rock Bet
last td
- Estimated edge
- 1.3%
- Fair odds
- +1018
- Starts
- Sep 27, 4:05 PM EDT
C
NFL
Deebo Samuel
+1200theScore
1st td
- Estimated edge
- 1.3%
- Fair odds
- +1013
- Starts
- Sep 27, 4:05 PM EDT
C
NFL
Trey McBride
+115theScore
Over 7.5 receptions
- Estimated edge
- 1.3%
- Fair odds
- +109
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Michael Wilson
-110DraftKings
Under 44.5 reception yds
- Estimated edge
- 1.1%
- Fair odds
- -115
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Luke Farrell
+6000Hard Rock Bet
1st td
- Estimated edge
- 1.1%
- Fair odds
- +3556
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Tyler Allgeier
+1200Hard Rock Bet
1st td
- Estimated edge
- 1.1%
- Fair odds
- +1038
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Marvin Harrison Jr.
-150theScore
Under 2.5 receptions
- Estimated edge
- 1.1%
- Fair odds
- -157
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Christian McCaffrey
-110theScore
Under 55.5 rush yds
- Estimated edge
- 1.1%
- Fair odds
- -115
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Mike Evans
+900DraftKings
1st td
- Estimated edge
- 1.0%
- Fair odds
- +806
- Starts
- Sep 27, 4:05 PM EDT
D
NFL
Jeremiyah Love
+900Fanatics
last td
- Estimated edge
- 1.0%
- Fair odds
- +805
- Starts
- Sep 27, 4:05 PM EDT