MLB game preview

St. Louis Cardinals at Pittsburgh Pirates

projected score, fair-odds context, available venue conditions, and current value for this matchup.

Game details

StartsSep 22, 2026, 6:41 PM EDT
Market coverage6 tracked opportunitiesUpdated Sep 21, 4:57 PM EDT

Market read

Matchup outlook

The market-implied score favors Pittsburgh Pirates 4.4–3.0 over St. Louis Cardinals, a 1.4-run margin. The consensus total is 7.4, with Pittsburgh Pirates -1.4 at home.

Current market

Best current game edges

Compare the current tracked price with Edge’s fair estimate. Sportsbook prices can move quickly.

A

MLB

St. Louis Cardinals @ Pittsburgh Pirates

+103DraftKings

Under 7

Estimated edge
5.1%
Fair odds
-119
Starts
Sep 22, 6:41 PM EDT
D

MLB

St. Louis Cardinals @ Pittsburgh Pirates

+160theScore

Pittsburgh Pirates -1.5

Estimated edge
1.1%
Fair odds
+153
Starts
Sep 22, 6:41 PM EDT

Player markets

Current player prop edges

Confirm player availability and the latest line before placing a bet.

C

MLB

Jared Jones

+105Hard Rock Bet

Over 1.5 pitcher earned runs

Estimated edge
2.0%
Fair odds
-103
Starts
Sep 22, 6:41 PM EDT
C

MLB

Andre Pallante

+100Fanatics

Over 15.5 pitcher outs

Estimated edge
1.2%
Fair odds
-105
Starts
Sep 22, 6:41 PM EDT
D

MLB

Andre Pallante

+115Fanatics

Over 5.5 pitcher hits allowed

Estimated edge
1.1%
Fair odds
+110
Starts
Sep 22, 6:41 PM EDT